First Authored Paper: Alicia Harracksingh
🔥 Hot Paper Alert! 🔥
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This week the UTM Biology department is celebrating the achievement of MSc student, Alicia Harracksingh, who had her first paper published recently in the Scientific Reports Journal.
Alicia's first published paper was recently featured in the Scientific Reports Journal. This study investigates the evolutionary interactions between Mint proteins and voltage-gated calcium (CaV) channels. Mint, an animal-specific scaffolding protein, has a conserved C-terminus with PDZ domains that mediate its binding to CaV2 channels. The research team demonstrates through in silico and experimental analyses that Mint-CaV2 interactions are conserved across various animal lineages, including cnidarians and placozoans. Furthermore, they demonstrated that sequence changes in CaV2 channel C-termini in early animals altered the structural determinants for the Mint-CaV2 interaction, while nevertheless retaining the capacity of these two proteins to interact.
Congrats, Alicia!
Follow this link to read the paper or click the link in bio for IG:
https://doi.org/10.1038/s41598-024-70652-8